prophylactic probiotics for prevention of necrotizing enterocolitis (nec) in low birth weight neonates; quality of the evidence
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prophylactic probiotics for prevention of necrotizing enterocolitis (nec) in low birth weight neonates
background probiotics are thought to interfere with the mechanisms involving in the pathogenesis of necrotizing enterocolitis in neonates. objectives this study was planned to assess the effect of prophylactic probiotics for the prevention of necrotizing enterocolitis in low birth weight neonates. patients and methods this prospective triple-blinded, interventional, randomized clinical trial en...
متن کاملProphylactic probiotics for prevention of necrotizing enterocolitis in very low birth weight newborns.
Our study showed that enteral administration of prophylactic probiotics in neonatal intensive care setup could significantly reduce morbidity due to necrotising enterocolitis in very low birth weight newborn. It also helps in establishing early full enteral feeding and reduces hospital stay.
متن کاملOral Probiotics Versus No Treatment for Prevention of Necrotizing Enterocolitis in Low Birth Weight Infants
Background: To study the utility of oral probiotics for preventing necrotizing enterocolitis (NEC) in low birth weight infants Methods: In this randomized controlled study preterm infants, weighing less than 1500 grams and who were fit to receive enteral feeds (Stable vitals, soft abdomen with normal bowel sounds and no nasogastric aspirate) were included. Infants were randomly assigned to two ...
متن کاملOral probiotics prevent necrotizing enterocolitis in very low birth weight neonates.
OBJECTIVE To test the hypothesis that normalizing the intestinal flora by administration of prophylactic probiotics would provide a natural defense, thereby reducing both the incidence and severity of necrotizing enterocolitis (NEC) in preterm neonates. STUDY DESIGN Neonates < or =1500 g birth weight were randomized to either receive a daily feeding supplementation with a probiotic mixture (B...
متن کاملProbiotics for the prevention of necrotizing enterocolitis.
Necrotizing enterocolitis (NEC) remains a significant cause of morbidity and mortality for low birth weight premature infants. Prematurity, ischemia, formula feeding, and bacterial colonization are risk factors for the self-perpetuating cycle of damaged intestinal epithelia, inflammation, bacterial entry, sepsis, and shock that characterizes NEC. Probiotics are food supplements containing live ...
متن کاملProbiotics and the prevention of necrotizing enterocolitis.
matory response of the immature intestinal immune system, resulting in rapidly evolving intestinal gangrene, perforation, sepsis, shock and death [1, 2, 4] . Probiotics have been shown to be able to modify both the intestinal microbiota as well as the intestinal immune response. On this background, several clinical trials have been carried out in order to investigate the potential role of probi...
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عنوان ژورنال:
archives of pediatric infectious diseasesجلد ۲، شماره ۲، صفحات ۲۳۱-۲۳۲
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